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. 2021 Nov 24;14:3603–3614. doi: 10.2147/JPR.S336773

Table 3.

Effect of CBD

CBD concentration (µM) 0 1 10 30 100
CBD response
Mean ± s.e.m
0 6.9 ± 5.5 45.6 ± 10.6 59.9 ± 10.6 74.3 ± 2.8
N (neurons) 6 (78) 6 (80) 6 (81) 6 (71) 6 (80)
Capsaicin response Mean ± s.e.m. 100.0 ± 4.7 62.6 ± 7 ** 25 ± 9.7 *** 18.6 ± 7.1 *** 9.99 ± 2.5 ***
N (neurons) 6 (78) 6 (80) 6 (81) 6 (71) 6 (80)

Notes: Data showing dose related responses to applied CBD, and reduction of capsaicin responses after CBD application. Pearson’s coefficient = −0.99. “N” indicates number of rats and the total number of neurons is in brackets. **P < 0.01, ***P < 0.001, Students T-Test.