Table 3.
Effect of CBD
CBD concentration (µM) | 0 | 1 | 10 | 30 | 100 |
CBD response Mean ± s.e.m |
0 | 6.9 ± 5.5 | 45.6 ± 10.6 | 59.9 ± 10.6 | 74.3 ± 2.8 |
N (neurons) | 6 (78) | 6 (80) | 6 (81) | 6 (71) | 6 (80) |
Capsaicin response Mean ± s.e.m. | 100.0 ± 4.7 | 62.6 ± 7 ** | 25 ± 9.7 *** | 18.6 ± 7.1 *** | 9.99 ± 2.5 *** |
N (neurons) | 6 (78) | 6 (80) | 6 (81) | 6 (71) | 6 (80) |
Notes: Data showing dose related responses to applied CBD, and reduction of capsaicin responses after CBD application. Pearson’s coefficient = −0.99. “N” indicates number of rats and the total number of neurons is in brackets. **P < 0.01, ***P < 0.001, Students T-Test.