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. 2021 Oct 25;101(1):101563. doi: 10.1016/j.psj.2021.101563

Table 10.

Effects of dietary supplemental with EOA on TLR signaling pathway-related genes expressions in the jejunum of broiler chickens challenged with NE.

Items Experimental design
SEM1 P-values2
A D E F G H
TLR2 1.01b 1.26ab 1.50a 0.9b 0.91b 0.75b 0.07 0.005
TLR-4 1.07b 1.66a 0.90bc 0.88bc 0.59bc 0.46c 0.09 <0.001
TRAF6 1.02ab 0.96ab 1.12a 0.759b 0.36c 0.46c 0.06 <0.001
MyD88 1.02 1.01 1.13 0.79 0.87 1.13 0.05 0.292
NF-κB 1.06a 0.90ab 0.50c 0.57c 0.39c 0.69bc 0.06 0.003
IL-1β 1.05 1.14 0.93 0.80 0.62 0.85 0.06 0.125
IL-8 1.38b 0.63c 0.48c 0.45c 1.02b 1.97a 0.18 0.079
IL-10 1.07 1.37 1.38 0.82 1.24 0.53 0.10 0.091
IFN-γ 1.01c 3.89a 2.39abc 2.06bc 3.13ab 2.90ab 0.25 0.009
TNFSF15 1.00abc 1.08ab 1.03abc 1.14a 0.79c 0.85bc 0.04 0.034
Tollip 1.02a 0.84ab 0.97a 0.73bc 0.57c 0.53c 0.04 <0.001
SOCS-1 1.06 1.23 1.32 1.19 1.19 1.11 0.09 0.979
SOCS-6 1.02b 0.92bc 1.41a 0.97bc 0.67c 0.67c 0.06 <0.001
A-20 1.02 1.06 1.33 1.10 1.43 0.93 0.09 0.558
PI3K 1.04a 0.73b 0.96ab 0.80ab 0.73b 0.69b 0.04 0.046
a,b,c,d

Means within the same row without a common superscript differ significantly (P < 0.05); A: uninfected and untreated control; D: infected and untreated control; E: infected birds fed basal diet supplemented with 250 mg/kg bacitracin methylene disalicylate (BMD, 15% purity) plus 90 mg/kg monensin; F: infected birds fed basal diet supplemented with 200 mg/kg EOA; G: infected birds fed basal diet supplemented with 500 mg/kg EOA; H: infected birds fed basal diet supplemented with 800 mg/kg EOA.

1

SEM, standard error of the mean. 2P-values represent the interaction between the dietary treatments.