Table 2.
Linear regression coefficients, 95% confidence intervals, and p-values for the models of EEsAI PRO as outcome in all patients.
| Model with eos/hpf as predictor | Coefficient [95% CI] | p-valueb |
|---|---|---|
| a coefficient for 10-cell increase in max eos/hpf in non-dilated patients | 2.69 (0.97, 4.40) | 0.002 |
| coefficient for 10-cell increase in max eos/hpf in patients dilated > 1 year prior to index endoscopy | 0.78 (−1.48, 3.05) | 0.494 |
| coefficient for 10-cell increase in max eos/hpf in patients dilated ≤ 1 year prior to index endoscopy | −1.64 (−4.07, 0.79) | 0.183 |
| Model with EREFS as predictor | Coefficient [95% CI] | p-value |
| coefficient for unit increase in EREFS in non-dilated patients | 1.88 (−0.14, 3.91) | 0.068 |
| coefficient for unit increase in EREFS in patients dilated > 1 year prior to index endoscopy | −2.30 (−5.03, 0.42) | 0.097 |
| coefficient for unit increase in EREFS in patients dilated ≤ 1 year prior to index endoscopy | −5.31 (−8.91, −1.71) | 0.004 |
The coefficient represents the change in the predicted EEsAI for 10-cell increase in max eos/hpf in non-dilated patients. For a 10-cell increase in eos/hpf score, the predicted EEsAI PRO increased by 2.69 in non-dilated patients.
P-value is testing whether the slope of the regression line in each dilation group is different from zero.
Abbreviations: CI, confidence interval; eos/hpf, esophageal eosinophilia per high-power field; EEsAI, eosinophilic esophagitis activity index; EREFS, endoscopic reference score.