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. 2021 Nov 26;11(11):e056436. doi: 10.1136/bmjopen-2021-056436

Table 2.

Laboratory test results among COVID-19 patients with LTOT compared with COVID-19 patients without LTOT

Type Before propensity score matching After propensity score matching
LTOT mean±SD (n) No LTOT mean±SD (n) P value LTOT mean±SD (n) No LTOT mean±SD (n) P value
Systolic blood pressure 126.92±20.88 (6751) 124.32±18.45 (115578) <0.001 126.92±20.88 (6745) 127.57±18.97 (4591) 0.092
Diastolic blood pressure 74.72±13.3 (6955) 74.5±12.25 (117093) 0.144 74.72±13.29 (6949) 75.1±12.64 (4635) 0.124
Leucocytes 8.08±5.37 (6249) 8.05±29.6 (81865) 0.935 8.08±5.37 (6245) 7.73±3.46 (3214) <0.001
Lymphocytes 23.52±12.25 (5244) 25.31±11.73 (73104) <0.001 23.52±12.25 (5238) 24.79±11.3 (2852) <0.001
Platelets 259.71±99.28 (6373) 263.86±91.06 (82724) <0.001 259.76±99.29 (6367) 256.82±84.74 (3300) 0.147
Serum creatinine 1.43±4.19 (6511) 1.01±1.99 (82058) <0.001 1.43±4.19 (6505) 1.19±1.33 (3715) <0.001
Blood urea nitrogen 19.42±15.94 (5363) 16.89±12.66 (66174) <0.001 19.4±15.93 (5357) 18.45±12.87 (3267) 0.004
Lactate dehydrogenase 374.05±680.51 (1800) 369.42±503.9 (17146) 0.721 374.17±680.87 (1798) 318.18±177.96 (628) 0.042
Alanine aminotransferase 40.4±194.16 (5764) 42.75±152.74 (67653) 0.275 40.42±194.26 (5758) 31.49±50.56 (2954) 0.014
Aspartate aminotransferase 51.18±447.66 (5755) 42.48±362.99 (67173) 0.087 51.21±447.89 (5749) 42.39±106.06 (2997) 0.231
Alkaline phosphatase 95.62±62.63 (5677) 80.31±48.37 (66328) <0.011 95.54±62.55 (5671) 84.65±42.9 (3036) <0.001
Serum ferritin 613.81±1870.26 (2614) 742.76±2742.34 (22438) 0.019 614.02±1870.59 (2613) 545.99±959.78 (1011) 0.271
Troponin I 0.38±3.32 (1338) 0.72±12.59 (6906) 0.332 0.39±3.33 (1334) 0.25±1.21 (299) 0.494
C reactive protein 46.33±67.13 (2644) 37.53±56.76 (25138) <0.001 46.32±67.14 (2642) 38.35±56.43 (906) <0.001

Measurement unit: leucocytes in 1000/μL; platelets in 1000/μL; serum creatinine in mg/dL; CRP in mg/L; lymphocytes, BUN in mg/dL; serum ferritin, troponin I in ng/mL; lactate dehydrogenase, alanine aminotransferase (ALT), aspartate aminotransferase, alkaline phosphatase (ALP) in units/L.

LTOT, long-term opioid therapy.