Table 4.

Association of PA Pathogen Characteristics and Mortality in Early Samples

PA Pathogen Characteristics, n = 156	30-d Mortality		90-d Mortality
	Unadjusted OR (95% CI)	Adjusteda OR (95% CI)	Unadjusted OR (95% CI)	Adjustedb OR (95% CI)
Elastase activity, per SD	1.67 (1.17-2.38)	1.56 (1.10-2.23)	1.62 (1.12-2.34)	1.55 (1.08-2.22)
Protease activity, per SD	1.58 (1.14-2.20)	1.46 (1.04-2.07)	1.39 (1.01-1.92)	1.30 (0.92-1.86)
Biofilm production,c per SD	1.03 (0.77-1.38)	1.01 (0.75-1.36)	1.10 (0.82-1.47)	1.05 (0.77-1.44)
MDR/XDRc	0.98 (0.56-1.72)	0.83 (0.39-1.78)	0.86 (0.51-1.48	0.72 (0.34-1.51)
Polymicrobiald	0.41 (0.23-0.73)	0.57 (0.27-1.22)	0.66 (0.39-1.12)	0.91 (0.44-1.87)

A logistic regression model was used to determine the association between PA pathogen factors and 30-d and 90-d mortality in early samples collected between 0 and 3 days from the index ICU admission date. The early and late subgroups were determined using a finite mixture model. CCI = Charlson Co-morbidity Index; MDR = multidrug-resistant; mSOFA = modified sequential organ failure assessment score; XDR = extensively drug resistant.

^aThe 30-d mortality model was adjusted for age, sex, and mSOFA.

^bThe 90-d mortality model was adjusted for age, sex, mSOFA, and CCI. P < .05 are in bold.

^cn = 154 for Biofilm production and n = 153 for MDR/XDR.

^dn = 154 for polymicrobial.