Table 5.

Association of PA Pathogen Characteristics and Mortality in Late Samples

PA Pathogen Characteristics, n = 82	30-d Mortality		90-d Mortality
	Unadjusted	Adjusteda	Unadjusted	Adjustedb
Elastase activity, per SD	0.79 (0.42-1.50)	0.80 (0.41-1.57)	0.71 (0.41-1.22)	0.67 (0.36-1.27)
Protease activity, per SD	0.97 (0.57-1.64)	0.98 (0.56-1.73)	0.75 (0.47-1.22)	0.69 (0.40-1.19)
Biofilm production, per SD	1.51 (0.82-2.77)	1.55 (0.82-2.94)	1.14 (0.64-2.02)	0.96 (0.52-1.77)
MDR/XDRc	1.33 (0.55-3.22)	1.10 (0.35-3.42)	2.79 (1.26-6.15)	3.41 (1.10-10.58)
Polymicrobialc	0.77 (0.33-1.81)	0.88 (0.31-2.54)	0.42 (0.20-0.89)	0.38 (0.14-1.09)

A logistic regression model was used to determine the association between PA pathogen factors and 30-d and 90-d ICU mortality in late samples collected ≥4 d from the index ICU admission date. The early and late subgroups were determined using a finite mixture model. CCI = Charlson Co-morbidity Index; MDR = multidrug-resistant; mSOFA = modified sequential organ failure assessment score; XDR = extensively drug resistant.

^aThe 30-d mortality model was adjusted for age, sex, and mSOFA.

^bThe 90-d mortality model was adjusted for age, sex, mSOFA, and CCI. P < .05 are in bold.

^cn = 81 for MDR/XDR and polymicrobial.