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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: J Nutr Biochem. 2021 Aug 15;99:108842. doi: 10.1016/j.jnutbio.2021.108842

Figure 5. Effect of curcumin on TGFβR2 and Smad2 stability, synthesis and expression.

Figure 5.

A) TGFβR2 and Smad protein stability (Western blot densitometry, n = 3/time) in control vs curcumin-treated (30 μM) MDA-SA cells concurrently treated with cycloheximide (CHX) to block protein synthesis. B) TGFβR2 and Smad protein synthesis (Western blot densitometry, n = 4/time) in control vs curcumin-treated (30 μM) MDA-SA cells pre-treated with cycloheximide for 24 h. C) TGFβR2 and Smad2 mRNA levels in curcumin-treated (30 μM, 16h) vs. control MDA-SA cells, reported as mean ± CI * p < 0.05, ** p < 0.01 vs. control.