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. Author manuscript; available in PMC: 2022 Jul 23.
Published in final edited form as: Behav Brain Res. 2021 Apr 25;410:113317. doi: 10.1016/j.bbr.2021.113317

Figure 2. Quantitative parameters of ultrasonic vocalizations (USVs) in male mice.

Figure 2.

Flurothyl seizures did not impact the quantity of USVs emitted in male mice, however, rapamycin-treated male mice emitted significantly less USVs compared to minocycline-treated mice and those that received the combined treatment (A). Rapamycin-treated mice also emitted USVs of significantly reduced duration compared to minocycline-treated mice and those that received the combined treatment (B). No significant effects were detected in the average peak frequency of USVs in male mice (C). Male mice that were treated with rapamycin emitted USVs with significantly reduced fundamental frequency compared to minocycline-treated mice (D). Control mice that received rapamycin emitted calls of significantly increased amplitude compared to control saline-treated mice (E). Data are expressed as mean ± standard error of the mean (SEM). Differences in lettering indicate significance between groups at the level of p < 0.05.