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. Author manuscript; available in PMC: 2022 Jul 23.
Published in final edited form as: Behav Brain Res. 2021 Apr 25;410:113317. doi: 10.1016/j.bbr.2021.113317

Figure 9. Hippocampal expression of mTOR signaling proteins in female mice.

Figure 9.

No effect of seizure administration or treatment was detected for p70S6K expression levels (A). There was a significant effect of treatment for S6, with female mice that received the combined treatment having significantly decreased expression levels compared to saline-treated and minocycline-treated mice, and rapamycin-treated mice having reduced expression compared to minocycline-treated mice (B). Mice that received rapamycin or the combined treatment had significantly downregulated levels of pS6(235,236) (C), % total pS6(235,236) (D), pS6(240,244) (E), or % total pS6(240,244) (F). No effect of seizure administration or treatment was detected for Akt (G), pAkt (H), or % total pAkt (I). Data are expressed as mean ± standard error of the mean (SEM). Differences in lettering indicate significance between groups at the level of p < 0.05.