Table 3.

Adjusted odds ratios (OR) for asthma risk factors and asthma diagnosis from main model and 2 sensitivity analyses^**

	Main Analysis			Second Asthma Diagnosis			Proximity cohort
	OR	95% CI	P-value	OR	95% CI	P-value	OR	95% CI	P-value
Race/ethnicity (ref non-Hispanic White)
Non-Hispanic Asian	1.13	1.05-1.21	< 0.001	1.12	1.03-1.21	0.006	1.26	1.10-1.45	0.001
Non-Hispanic Black	1.67	1.62-1.73	< 0.001	1.68	1.61-1.74	< 0.001	1.77	1.63-1.92	< 0.001
Hispanic	1.2	1.15-1.26	< 0.001	1.3	1.23-1.37	< 0.001	1.26	1.11-1.42	< 0.001
Missing	0.95	0.91-0.99	0.026	0.99	0.94-1.04	0.651	1.12	0.97-1.30	0.128
Other	1.1	1.00-1.21	0.047	1.14	1.02-1.26	0.016	1.31	1.06-1.62	0.012
Male gender	1.18	1.15-1.21	< 0.001	1.16	1.13-1.19	< 0.001	1.09	1.05-1.14	< 0.001
Prematurity (<34 weeks)	1.21	1.15-1.27	< 0.001	1.17	1.11-1.24	< 0.001	1.09	1.00-1.18	0.04
Food allergy	1.27	1.21-1.32	< 0.001	1.27	1.22-1.33	< 0.001	1.28	1.18-1.39	< 0.001
Allergic rhinitis	2.01	1.96-2.08	< 0.001	2.05	1.99-2.12	< 0.001	1.83	1.72-1.95	< 0.001
Eczema	1	0.97-1.02	0.747	1.05	1.02-1.08	< 0.001	1.2	1.15-1.25	< 0.001
Any wheeze episode	28.56	27.42-29.75	< 0.001	48.92	45.69-52.38	< 0.001	30.99	28.49-33.72	< 0.001
Additional wheeze episodes	1.37	1.36-1.38	< 0.001	1.47	1.46-1.48	< 0.001	1.54	1.51-1.56	< 0.001
Any cough episodes	1.01	0.97-1.03	0.95	1.01	0.98-1.04	0.635	0.92	0.88-0.97	< 0.001
Additional cough episodes	1.06	1.04-1.07	< 0.001	1.03	1.01-1.04	< 0.001	1	0.98-1.03	0.79
Proportion diagnosed with asthma		21.41%			17.14%			27.72%
Variance from GLMM†		0.1413			0.1621			0.0047
ICC‡		0.0412			0.0470			0.0014

^**A11 analyses adjusted for age. See Supplemental Table 2 in Appendix for ORs for 3-month age intervals.

^†Generalized linear mixed model

^‡Intraclass correlation coefficient