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. 2021 Nov 8;10(4):45. doi: 10.3390/antib10040045

Figure 5.

Figure 5

Dose-dependent post-exposure protection against SARS-CoV-2 infection of K18-hACE2 mice. Animals were intranasally infected with SARS-CoV-2 and treated two days later with either 100 µg/mouse (full lines) or 10 µg/mouse (dashed lines) of MD65 (n = 6 for each group), MD65-AG (n = 6 for each group) or with PBS as control (n = 8). (A) Kaplan–Meyer surviving curves. (B) Bodyweight profiles (empty and filled circles indicate treatment with 10 or 100 µg/mouse, respectively; data represents mean ± SEM).