(a) Setup of compact SPR biosensor (left) and the photo and schematic diagram of the biochip (right). (b) Sensing mechanism of compact SPR biosensor. (c) Calibration of sensing performance of compact SPR biosensor with 1%, 2%, and 3% glycerol solutions. (d) Real-time SPR response upon the addition of PBS, PEG mixture, Neutravidin, and anti-EGFR antibodies during the biochip surface modification.