Fig. 1.

The photo (a) and the schematic diagram (b) of the microfluidic biochip for exosome immunomagnetic isolation (1), on-chip exosome lysis, and protein immunoprecipitation (2) and intra-vesicular protein detection via chemifluorescence-assisted immunoassays (3). c The setup and detection mechanism of ExoSearch biochip. Antibody-conjugated magnetic beads were used to capture exosomes from plasma samples. Multiplexed exosomal protein detection was realized by multi-color fluorescence imaging. Figures are adapted from Refs. (28) and (29) with permission from the Royal Society of Chemistry.