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. 2021 Nov;60(6):616–629. doi: 10.30802/AALAS-JAALAS-20-000154

Table 5.

Original biochemical reference intervals (RI) in lithium-heparinized plasma from 59 healthy adult Southern giant pouched rats (Cricetomys ansorgei) before outlier removal. Results were obtained with the Hitachi P Modular (most analytes) and Cobas 501 (lipase) biochemical analyzers. Only analytes for which outliers were removed from the final RIs (Table 7) are shown. The reason for each outlier removal is provided below the table. None of the data required transformation.

Descriptive statistics RI with 90% CI
Analyte Units Mean Median SD Min/Max RI Lower Limit Upper Limit n Distribution
Potassium mmol/L 4.9 4.8 0.5 4.0-6.5 4.1-6.2 4.0-4.2 5.6-6.5 59 NG
Sodium:Potassium 30 30 3 22-36 23-35 22-25 34-36 59 NG
Bicarbonate mmol/L 31 31 3 20-37 23-37 20-27 35-37 59 NG
Anion gap mmol/L 19 19 4 9-38 12-32 9-15 23-38 59 NG
CK IU/L 361 331 115 228-877 232-767 228-238 544-877 59 NG
Triglycerides mmol/L 1.2 1.0 0.6 0.5-4.2 0.5-3.5 0.5-0.7 1.9-4.2 59 NG

Min/Max: Minimum/Maximum; CK: Creatine kinase; NG = Nongaussian

Outliers removed

Potassium and Sodium:Potassium: One outlier; #53, K 6.5 mmol/L – Possible outlier on program and visually.

Bicarbonate and anion gap: One outlier; #23, bicarbonate 20 mmol/L; anion gap 38 mmol/L – Outlier on program and visually.

CK: One outlier; #65, CK 877 IU/L – Outlier on program and visually.

Triglycerides: One outlier; #38, triglycerides 4.2 mmol/L – Outlier on the program and visually.