Table 9.
Biochemical variables partitioned by sex for lithium-heparinized plasma samples from 59 wild-caught Southern giant pouched rats (Cricetomys ansorgei)
| Male (n = 24–35) | Female (n = 23 or 24) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Variable | Unit | Mean ± 1 SD | Median | Range | Mean ± 1 SD | Median | Range | ||
| Sodium | mmol/L | 143 ± 3 | 142 | 137 to 149 | 144 ± 2 | 144 | 141 to 150 | ||
| Potassium | mmol/L | 4.9 ± 0.4 | 4.8 | 4.1 to 5.9 | 4.7 ± 0.4 | 4.6 | 4.0 to 5.6 | ||
| Sodium:potassium | 29 ± 3 | 30 | 24 to 34 | 31 ± 3 | 31 | 25 to 36 | |||
| Chloride | mmol/L | 98 ± 3 | 98 | 92 to 104 | 99 ± 2 | 99 | 95 to 101 | ||
| Bicarbonate | mmol/L | 31 ± 2 | 31 | 27 to 34 | 32 ± 2 | 32 | 29 to 37 | ||
| Anion gap | mmol/L | 20 ± 3 | 20 | 14 to 28 | 18 ± 3 | 19 | 9 to 23 | ||
| Urea nitrogen | mmol/L | 6.8 ± 1.4 | 6.8a | 4.6 to 9.6 | 8.9 ± 1.4 | 9.3 | 3.6 to 11.8 | ||
| Creatinine | umol/L | 35.4 ± 8.8 | 35.4 | 17.7 to 79.6 | 35.4 ± 8.8 | 35.4 | 26.5 to 44.2 | ||
| Calcium | mmol/L | 2.7 ± 0.1 | 2.7 | 2.6 to 2.9 | 2.8 ± 0.1 | 2.8 | 2.6 to 2.9 | ||
| Phosphate | mmol/L | 1.2 ± 0.2 | 1.2 | 0.7 to 1.9 | 1.2 ± 0.3 | 1.2 | 0.8 to 1.9 | ||
| Magnesium | mmol/L | 0.6 ± 0.1 | 0.6 | 0.5 to 0.7 | 0.6 ± 0.1 | 0.6 | 0.5 to 0.7 | ||
| Total protein | g/L | 72 ± 6 | 71 | 64 to 89 | 73 ± 6 | 72 | 62 to 85 | ||
| Albumin | g/L | 28 ± 3 | 29 | 24 to 33 | 29 ± 3 | 29 | 22 to 34 | ||
| Globulins | g/L | 44 ± 08 | 40 | 35 to 65 | 44 ± 9 | 42 | 31 to 62 | ||
| Albumin:globulins | 0.7 ± 0.2 | 0.7 | 0.4 to 0.9 | 0.7 ± 0.2 | 0.7 | 0.4 to 1.0 | |||
| Glucose | mmol/L | 8.4 ± 1.8 | 8.0 | 5.6 to 11.7 | 8.1 ± 1.5 | 7.8 | 5.8 to 11.0 | ||
| ALT | IU/L | 22 ± 11 | 19 | 11 to 68 | 20 ± 6 | 19 | 13 to 41 | ||
| AST | IU/L | 22 ± 9 | 21 | 11 to 53 | 25 ± 9 | 22 | 15 to 30 | ||
| ALP | IU/L | 97 ± 32 | 97 | 48 to 171 | 90 ± 25 | 80 | 57 to 142 | ||
| GGT | IU/L | 1 ± 1 | 1a | 1 to 5 | 2 ± 1 | 3 | 1 to 4 | ||
| Total bilirubin | µmol/L | 0.3 ± 0.7 | 0 | 0 to 1.7 | 1.7 ± 1.7 | 0.1 | 0 to 13.7 | ||
| Direct bilirubin | µmol/L | 0 | 0 | 0 | 0.3 ± 0.7 | 0 | 0 to 1.7 | ||
| Indirect bilirubin | µmol/L | 0.3 ± 0.7 | 0 | 0 to 1.7 | 1.7 ± 1.7 | 0 | 0 to 1.7 | ||
| Creatine kinase | IU/L | 327 ± 79 | 322 | 228 to 657 | 390 ± 101 | 390 | 235 to 552 | ||
| Iron | µmol/L | 30.3 ± 8.4 | 30.8 | 14.1 to 50.8 | 34.2 ± 11.3 | 33.3 | 22.4 to 64.3 | ||
| Total iron-binding capacity | µmol/L | 65.7 ± 10.2 | 66.4 | 48.0 to 84.5 | 73.2 ± 9.0 | 69.8 | 62.3 to 93.6 | ||
| Saturation | % | 46 ± 10 | 46 | 22 to 67 | 47 ± 12 | 43 | 33 to 84 | ||
| Amylase | IU/L | 783 ± 152 | 760 | 458 to 1097 | 791 ± 144 | 789 | 569 to 1058 | ||
| Lipase | IU/L | 11 ± 2 | 11 | 7 to 16 | 13 ± 4 | 12 | 9 to 27 | ||
| Cholesterol | mmol/L | 3.2 ± 0.9 | 2.9 | 1.8 to 5.5 | 3.2 ± 0.6 | 3.2 | 1.8 to 4.7 | ||
| Triglycerides | mmol/L | 1.2 ± 0.4 | 1.0 | 0.5 to 2.7 | 1.1 ± 0.3 | 1.0 | 0.5 to 2.1 | ||
| Nonesterified fatty acids | mmol/L | 0.26 ± 0.07 | 0.25 | 0.13 to 0.43 | 0.26 ± 0.11 | 0.22 | 0.11 to 0.49 | ||
Data were obtained by using biochemical analyzers. Outliers identified during reference interval determination were excluded from this analysis, resulting in the differing animal numbers.
a
Medians were significantly different from those for female rats after the application of experimental-wise correction (P < 0.0016) for the number of measurands (n = 32).