Table 2.

Incidence rates of diabetes-related end-stage kidney disease and incidence trend analysis among adults aged ≥18 years, by race or ethnicity and age group — United States, 2000–2016.

	Incidence Rate (per 100,000 adults)		Percent change	Overall trend		Initial trend			Subsequent trends
Age (years)	2000	2016		AAPC (95% CI)	P	Years	APC (95% CI)	P	Years	APC (95% CI)	P
AIANs*
≥18†	66.7	31.2	−53	−4.5 (−5.9, −3.0)	<0.001	2000–13	−5.6 (−6.4, −4.8)	<0.001	2013–16	0.7 (−7.2, 9.3)	0.85
18–44	7.7	7.6	−1	−0.8 (−7.2, 6.0)	0.81	2000–09	1.1 (−2.3, 4.5)	0.49	2009–12	−10.8 (−38.1, 28.4)	0.49
									2012–16	2.9 (−8.3, 15.5)	0.58
45–64	108.3	46.6	−57	−4.5 (−6.2, −2.8)	0.002	2000–13	−5.8 (−6.7, −4.8)	<0.001	2013–16	1.2 (−8.0, 11.4)	0.79
65–74	231.2	92.8	−60	−5.8 (−7.7, −3.8)	<0.001	2000–12	−7.6 (−9.0, −6.2)	<0.001	2012–16	−0.0 (−7.7, 8.3)	0.99
≥75	119.3	61.9	−48	−4.2 (−5.7, −2.8)	<0.001	2000–16	−4.2 (−5.7, −2.8)‡	<0.001	--	--	--
Asians*
≥18†	19.8	19.7	−1	−0.0 (−2.1, 2.1)	1.00	2000–09	0.0 (−1.0, 1.1)	0.94	2009–12	−2.4 (−12.9, 9.3)	0.63
									2012–16	1.7 (−1.9, 5.4)	0.31
18–44	1.2	2.0	64	4.3 (3.0, 5.5)	<0.001	2000–16	4.3 (3.0, 5.5)‡	<0.001	--	--	--
45–64	19.6	21.0	7	−0.5 (−1.1, 0.2)	0.17	2000–16	−0.5 (−1.1, 0.2)‡	0.17	--	--	--
65–74	75.6	61.1	−19	−1.3 (−2.0, −0.7)	0.001	2000–16	−1.3 (−2.0, −0.7)‡	0.001	--	--	--
≥75	81.2	85.7	6	0.3 (−0.2, 0.8)	0.24	2000–16	0.3 (−0.2, 0.8)‡	0.24	--	--	--
Blacks*
≥18†	56.2	44.7	−20	−1.6 (−2.4, −0.8)	<0.001	2000–08	−0.7 (−1.3, −0.0)	0.048	2008–12	−4.3 (−7.1, −1.4)	0.009
									2012–16	−0.6 (−2.5, 1.3)	0.49
18–44	8.0	10.3	30	1.8 (1.1, 2.6)	<0.001	2000–07	4.2 (2.7, 5.7)	<0.001	2007–16	0.1 (−0.9, 1.0)	0.91
45–64	82.0	60.2	−27	−2.0 (−2.8, −1.1)	<0.001	2000–08	−1.5 (−2.2, −0.8)	0.001	2008–12	−4.6 (−7.7, −1.4)	0.01
									2012–16	−0.2 (−2.2, 1.9)	0.82
65–74	188.0	129.8	−31	−2.6 (−3.5, −1.6)	<0.001	2000–08	−1.3 (−2.1, −0.5)	0.005	2008–12	−5.8 (−9.2, −2.3)	0.005
									2012–16	−1.7 (−4.0, 0.6)	0.12
≥75	131.9	118.8	−10	−1.1 (−1.6, −0.7)	<0.001	2000–16	−1.1 (−1.6, −0.7)‡	<0.001	--	--	--
Hispanics*
≥18†	50.0	33.3	−33	−2.1 (−2.4, −1.8)	<0.001	2000–16	−2.1 (−2.4, −1.8)‡	<0.001	--	--	--
18–44	3.9	4.4	12	1.1 (0.1, 2.0)	0.03	2000–03	−1.4 (−5.3, 2.7)	0.46	2003–09	4.0 (2.2, 5.9)	0.001
									2009–16	−0.4 (−1.5, 0.7)	0.42
45–64	68.6	44.1	−36	−2.2 (−2.4, −1.9)	<0.001	2000–16	−2.2 (−2.4, −1.9)‡	<0.001	--	--	--
65–74	176.9	110.9	−37	−2.9 (−3.2, −2.6)	<0.001	2000–16	−2.9 (−3.2, −2.6)‡	<0.001	--	--	--
≥75	143.4	97.9	−32	−1.7 (−2.3, −1.2)	<0.001	2000–16	−1.7 (−2.3, −1.2)‡	<0.001	--	--	--
Whites*
≥18†	15.4	17.0	10	0.6 (0.3, 1.0)	0.01	2000–06	0.8 (0.2, 1.3)	0.01	2006–12	−0.5 (−1.2, 0.2)	0.16
									2012–16	2.1 (1.1, 3.2)	0.001
18–44	3.0	3.2	9	0.7 (−0.0, 1.4)	0.06	2000–05	−1.3 (−3.3, 0.7)	0.19	2005–16	1.6 (1.0, 2.2)	<0.001
45–64	20.7	23.3	13	0.8 (0.6, 1.1)	<0.001	2000–11	0.3 (0.1, 0.6)	0.009	2011–16	1.9 (1.1, 2.7)	<0.001
65–74	51.3	50.7	−1	−0.3 (−0.8, 0.3)	0.34	2000–06	0.2 (−0.5, 1.0)	0.54	2006–12	−2.0 (−2.9, −1.0)	0.002
									2012–16	1.6 (0.2, 3.1)	0.03
≥75	37.3	46.2	24	1.4 (0.7, 2.0)	<0.001	2000–05	3.6 (2.3, 4.9)	<0.001	2005–12	−0.7 (−1.6, 0.3)	0.16
									2012–16	2.2 (0.3, 4.1)	0.03

AIANs=American Indians and Alaska Natives; APC=annual percentage change; AAPC=average annual percentage change; CI=confidence interval.

^*Racial groups include people of Hispanic and non-Hispanic origin; Hispanics may be of any race.

^†Age-adjusted based on the 2000 US standard population.

^‡APC=AAPC (i.e., 0 joinpoints).