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. 2021 Nov 29;38:100533. doi: 10.1016/j.epidem.2021.100533

Fig. 4.

Fig. 4

Epidemic growth rate estimates from mechanistic model fits to population-level Ct distributions across the first wave of COVID-19 in three Madagascar regions. (A.) Comparison of COVID-19 epidemic growth rates from March-September 2020, estimated from IPM (blue) and publicly reported (gray) case count data using EpiNow2 (Abbott et al., 2020a) with estimates derived from Gaussian process (GP; red) mechanistic model fit to the time series of Ct distributions (Fig. 3A). Median growth rates are shown as solid lines, with 50% quantile on case-based estimates and 95% quantile of the posterior distributions from Ct-based estimates in corresponding sheer shading. (B.) Growth rate estimates from individual SEIR Ct-model fits to each Ct-distribution shown in Fig. 3A; median growth rates are given as horizontal dashes, with the 95%, 70%, 50%, and 20% of the posterior distribution indicated by progressively darker coloring. Estimates > 0 (indicating growing epidemics) are depicted in gold and < 0 (indicating declining epidemics) in purples. (C.) Raw case count data from the time series (dark = IPM data; light = publicly reported data) is shown for reference. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)