Fig. 2.

Macrophages subgroup classification. (A) All macrophages were further clustered into M1-like macrophages and M2-like macrophages. (B) The fraction of cells originated from different groups (Healthy controls, Medium patients and Severe patients). (C) Expression of canonical marker genes used for cell subtype annotation. (D) Enriched terms for each of three ontologies revealed by Gene Ontology (GO) enrichment results of M1-like macrophages. (E) Most enriched KEGG pathways revealed by differentially expressed genes of M1-like macrophages.