Table 5.

Commercially available hydrogel product.

S.No.	Product	Product Manufactured by/Marketed by	Type of Hydrogel	Active Component	Indications	Reference
1	AquaDerm™	DermaRite	Hydrogel sheet	2-Acrylamido-2 methyl-1 propane sulfonic acid sodium, Propylene Glycol, Poly (ethylene glycol) dimethacrylate, 2-Hydroxy-2-methylpropiophenone with 38–55% water	Minor burns, pressure ulcers and radiation tissue damage	[124]
2	DermaSynTM		Amorphous hydrogel		Acute/chronic partial and full thickness wounds/ulcers having minimal exudate
3	DermaGauze™		Hydrogel impregnated gauze dressing	Acrylate polymer	Acute/chronic partial and full thickness wounds having minimal exudate and wounds with tunneling or sinus tracts
4	DermaSyn/Ag™		Water-based antibacterial silver Wound gel	Silver	Venous ulcers, tissue trauma, pressure ulcers, diabetic ulcers, surgical incisions Thermal burns, etc.
5	Intrasite® GEL	Smith and Nephew	Hydrogel	Carboxymethyl cellulose and propylene glycol	Ease gentle, effective autolytic debridement to prepare the wound bed in all types of wounds	[125]
6	Suprasorb® G	Lohmann and Rauscher Global	Hydrogel film	Water (70%), acrylic polymers based on a taurate derivative, polyethylene, phenoxyethanol, transparent polyethylene carrier film	Used for the management of the first and second degree burns, dry fractures, ulcer of the lower leg, pressure ulcer, etc.	[126]
7	Neoheal®	Kikgel	Hydrogel sheet	Water (90%), polyvinylopyrrolidone, polyethylene glycol and agar, crosslinked by a beam of electrons.	Burns, ulcerations, bedsores and all types of skin damages where humid medium is favourable	[127]
8	Woun’Dres® Collagen Hydrogel	Coloplast	Collagen Hydrogel	Polymers such as carbomer and collagen	Dry wounds and eschar	[128]
9	Purilon®			Water, calcium alginate and sodium carboxymethyl cellulose	First and second degree burns, leg ulcers, pressure ulcers, non-infected diabetic foot ulcers
10	Simpurity®	Safe n’Simple	Absorbent hydrogel sheets	water, polyethylene oxide, polyvinyl alcohol, acrylate, polyurethane	Wounds with minimal to no exudate, skin burns and dry scabs	[129]
11	SimpurityHydroGel®		Impregnated Gauze Wound Dressings		First and second degree burns, pressure sores and leg ulcers
12	ProfiDerm®	Dr. Derm Professional	Hydrocollagen face gel	Sea collagen and hyaluronic acid	Nourishes, hydrates, soothes skin, helps to regenerate the skin of the face, ↑ the elasticity and tones the tissues	[130]
13	Advanced génifique light pearl hydrogel melting 360 eye mask	Lancome Paris	Hydrogel eye mask		↓ the appearance of undereye bags, puffy eyes, undereye circles and rejuvenate the eye area	[131]
14	Advanced génifique hydrogel melting sheet mask		Hydrogel sheet mask	Water, glycerine, polyacrylate-13, bifidus extract	Moisturized face skin, and make it radiant, smoother, shiny and healthy	[132]
15	Water bomb hydrogel mask	Moria	Hydrogel mask	Sodium polyacrylate, glycerine, cellulose gum, water	Restore hydration at a deeper level, soothesand rejuvenate the skin	[133]
16	EautraSil™	Miacare™	Silicone Hydrogel Contact Lens	Hyaluronic Acid and Sodium Alginate	Effectively prevent hypoxia-related complications (corneal neovascularization, redness, and corneal epithelium-aging)	[134]
17	Confidence		Silicone Hydrogel Contact Lens with Dot Matrix Colour Printing Technology	Hyaluronic Acid and Sodium Alginate	Long lasting comfort	[135]
18	Charcoal Hydrogel under eye mask	ELF cosmetics	Hydrogel mask	Charcoal Powder, Green Tea Extract, Lavender Extract	Under eye skin protection and rejuvenation	[136]
19	SEVEN RX®	Mark’ennovy	Hydrogel lens	Bioinspired silicone hydrogel lens	Short sight and long sight	[137,138]
20	Gentle 59	Mark’ennovy	Bio-inspired hydrogel lens		Short sight and long sight	[137]
21	MaxvueHiToric®	Maxvue vision	Silicone hydrogel	Hyaluronic Acid	Astigmatism	[137]
22	ACTIVHEAL® HYDROGEL	Advanced medical solution Ltd.	Amorphous gel	A primary wound dressing contains 85% water	Dry and sloughy wounds with zero to low exudate such as pressure ulcers, leg ulcers, cavity wounds, graft at donor sites, post op surgical wounds, lacerations and abrasions	[139]
23	Nu-Gel® Hydrogel with Alginate	Systagenix wound management	Hydrogel with alginate	Alginate	Helps in management of chronic wounds through all stages of healing. Manage dry, encrusted and necrotic, sloughy, granulating andepithelialising wounds.	[140]
24	SUPPRELIN® LA	Endo Pharmaceuticals, USA	Implant	Histrelin acetate	Treatment of children having central precocious puberty	[141]
25	Cervidil®	Ferring Pharmaceuticals, Inc.	Cervidil (dinoprostone) Vaginal Insert	crosslinked polyethylene oxide/urethane polymer, dinoprostone	Initiation and/or continuation of cervical maturement in pregnant women	[142]
26	SQZgel™	MacroMed	Controlled-release oral tablets	chitosan and polyethylene glycol	Hypertension	[143]
27	Mebiol® Gel	Cosmo Bio co ltd	Thermoreversible hydrogel	poly(N-isopropylacrylamide) and poly(ethylene glycol)	High transparency for cell observation, stem cell culture, cell implantation, organ/tissue regeneration, drug delivery, and non-cell culture applications	[144]
28	Gelrin C™	Regentis Biomaterial Ltd.	Photo crosslinked hydrogel	polyethylene glycol and human fibrinogen protein	projected for the reparation of focal defects in cartilage and/or osteochondral defects	[145]
29	Mebiol® Gel	Cosmo Bio	Thermoreversible Hydrogel	Poly (N- isopropylacrylamide) and POLY glycol ethylene	Cell implantation, organ and tissue regeneration, stem cell culture, drug delivery, and non-cell culture applications	[146]
30	HyStem® Hydrogel	ESI BIO	Hyaluronic acid UV light-controlled system	hyaluronic acid	3D cell culture for tissue engineering purposes and 3D printing applications	[147]
31	Corning® PuraMatrix™	Corning Incorporated Life sciences	Peptide hydrogel	-	3D cell culture used for stem cell proliferation, tumor cell migration and invasion, and in vivo analysis of tissue regeneration	[148]
32	Biogelx™	Bioglex Ltd.	Simple, short self-assembling peptides	-	Create an optimal environment for the culture of a variety of cell types, deliver synthetic yet biologically-relevant alternatives to animal-derived 3D matrices for example matrigel and collagen	[149]
33	SpaceOAR®	Boston scientific	Absorbable Injectable hydrogel	-	Imaging of cancerous cells and protecting healthy cells from radiation induced damage	[150]
34	Bulkamid®	Contura International	Soft injectable, transparent, hydrophilic gel	Synthetic polyacrylamide and water	Stress urinary incontinence	[151]
35	Symphony®	Cypre’s	Stimuli–responsive hydrogels as sensors	3D photolithographic instrument	Animal cell culture, 3D imaging, iPSCs, ESc cell lines, etc.	[152]
36	Valleylab™	Medtronic	Covalent anchored coatings	Chitosan-hyaluronic acid-based hydrogel catheter	Postoperative adhesion	[153]
37	Bolt Bis-Tris Plus Gels	Thermo Fisher	Bioassay matrices(gel)	Polyacrylamide gels	Western blot transfer and analysis	[154]
38	Tadpole™	Nervena®	Hydrogel electrode	Ionically conductive hydrogels	Use in Parotidectomy and otologic Surgery