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. 2021 Nov 12;28(6):4645–4654. doi: 10.3390/curroncol28060392

Table 3.

Proposed additional evidence that should be included in the reassessment process.

Evidence Categories Elements
Clinical evidence Performance status
Dose delays and dose intensity
Long-term toxicity
Sub-groups that may benefit less from treatments
Patient values Patient experiences and expectations
Patient-reported outcomes
Caregiver inputs
Quality of Life (QoL) collected using validated tools
Economic evidence Quality adjusted life years
Utility values
ICER using confidential prices
Implementation & Feasibility Disease-specific treatment maps to describe current treatment sequencing and how sequencing might change dependent of the outcome of the reassessment
Resource reallocation: where would the resources be reallocated from?

Abbreviations: ICER, incremental cost-effectiveness ratio; QoL, Quality of Life.