Table 1.
Characteristics of patients with incident invasive cutaneous melanoma in the GEM study (n = 3285) 1.
| Characteristic | No. (%) |
|---|---|
| Median age at most recent diagnosis (IQR), years | 58 (46–70) |
| Sex | |
| Male | 1827 (55.6) |
| Female | 1458 (44.4) |
| Lesion status | |
| First-order primary melanoma | 2458 (74.8) |
| Higher-order primary melanoma | 827 (25.2) |
| Anatomic site | |
| Head/neck | 565 (17.2) |
| Trunk | 1437 (43.7) |
| Upper extremities | 595 (18.1) |
| Lower extremities | 688 (20.9) |
| Histologic subtype | |
| Superficial spreading | 2144 (65.3) |
| Nodular | 275 (8.4) |
| Lentigo maligna | 377 (11.5) |
| Unclassified/other 2 | 489 (14.9) |
| Breslow thickness, mm | |
| Median (IQR) | 0.70 (0.44–1.26) |
| 0.01–1.00 | 2195 (66.8) |
| 1.01–2.00 | 592 (18.0) |
| 2.01–4.00 | 276 (8.4) |
| >4.00 | 144 (4.4) |
| Missing | 78 (2.4) |
| Ulceration | |
| Absent | 2392 (72.8) |
| Present | 225 (6.8) |
| Missing | 668 (20.3) |
| Mitoses | |
| Absent | 1544 (47.0) |
| Present | 1081 (32.9) |
| Missing | 660 (20.1) |
| Tumor-infiltrating lymphocyte (TIL) grade | |
| Absent | 567 (17.3) |
| Nonbrisk | 1658 (50.5) |
| Brisk | 385 (11.7) |
| Missing | 675 (20.5) |
Abbreviations: GEM, Genes, Environment and Melanoma; No., number; IQR, interquartile range. 1 Limited to individuals of European origin with incident invasive first- or higher-order primary melanoma. Percentages may not sum to 100 because of rounding of decimals. 2 Other includes acral lentiginous, spindle cell, nevoid, and Spitzoid melanomas.