Table 4.
Composition, experimental vs. predicted value with percentage error of optimized α-MNG-PLGA NPs.
| Variables | Optimum Composition | Response | Observed Value of Response | Predicted Value of Response | Percentage Error |
|---|---|---|---|---|---|
| X1 | 3.39 % w/v | Y1 | 168.06 ± 17.02 | 150.87 | 11.39 |
| X2 | 1.82 % w/v | Y2 | 0.201 ± 0.01 | 0.214 | −6.07 |
| X3 | 8.79 min | Y3 | 84.26 ± 8.23 | 79.16 | 6.44 |
Predicted error (%) = (observed value − predicted value)/predicted value×100%. X1: Polymer concentration (% w/v); X2, Surfactant concentration (% w/v), X3: Sonication time; Y1: Particle size (nm), Y2: PDI, Y3: Entrapment efficiency (%).