Fig. 3.
Inflammatory response to treatment with KCO and KCO-degrading bacteria in mouse colon and rectum. A: Photomicrographs of representative H&E-stained colon and rectal samples. Scale bar, 200 mm. B and C: Histopathological indexes reflect inflammation severity in the colon and rectum, respectively. Results are expressed as mean ± SEM (n = 6). Tissue samples were collected from GF, GFK (5% KCO), GN (5 × 108 CFU of B. xylanisolvens and E. coli), and GNK (5% KCO plus 5 × 108 CFU of B. xylanisolvens and E. coli) treatment groups in germ-free Kunming mice. SEM: standard error of the mean; GF, germ free control group.