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Surgery, SRS, and EGFR-TKI in the treatment of NSCLC brain metastases. Axial T1 with contrast MRI of a 49-yr-old female presenting with brain metastases from EGFR-mutated NSCLC (A) prior to surgical resection, (B) after surgical resection and starting TKI, and (C) 3 mo after SRS and adjuvant TKI. Red arrow shows the initial surgical lesion and the postoperative resection cavity. Blue arrow shows an additional nonsurgical lesion that also shows response to TKI and SRS.
