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. 2021 Nov 4;6(4):93. doi: 10.3390/jfmk6040093

Table 6.

Maximal oxygen consumption VO2 (mL/min/kg) at rest with and without L-carnitine supplementation and after exercise with and without L-carnitine supplementation.

Authors Carnitine Dosage N1 N2 Mean 1 SD 1 Mean 2 SD 2 SMD SE 95% CI t p Weight (%) Test for Heterogeneity
Fixed Random
Chun 2011 2 g/d, 4 w 6 6 57.07 3.07 57.52 3.42 −0.128 0.533 −1.316 to 1.061 7.72 7.72 Q 6.3892
Chun 2011 3 g/d, 4 w 6 6 62.06 7.29 60.00 6.16 0.282 0.536 −0.912 to 1.476 7.65 7.65 DF 10
Chun 2011 4 g/d, 4 w 6 6 59.33 7.57 67.26 7.66 −0.961 0.568 −2.226 to 0.304 6.82 6.82 Significance level p = 0.7816
Chun 2011 5 g/d, 4 w 6 6 59.78 6.47 63.64 4.86 −0.622 0.548 −1.843 to 0.598 7.32 7.32 I2 (inconsistency) 0.00%
Chun 2011 6 g/d, 4 w 6 6 59.90 4.88 61.20 4.44 −0.257 0.535 −1.450 to 0.936 7.67 7.67 95% CI for I2 0.00 to 37.99
Greig 1987 2 g/d, 2 w 9 9 41.4 7.5 41.6 8.8 −0.0233 0.449 −0.975 to 0.928 10.90 10.90
Greig 1987 2 g/d, 4 w 10 10 45.2 12.0 43.6 12.0 0.128 0.429 −0.773 to 1.028 11.95 11.95
Marconi 1985 4 g/d, 2 w 6 6 54.5 3.7 57.8 4.7 −0.720 0.553 −1.951 to 0.511 7.19 7.19
Parandak 2014 2 g/d, 2 w 11 10 22.4 0.8 23.0 0.6 −0.809 0.438 −1.724 to 0.107 11.47 11.47
Vecchiet 1990 2 g/d, one time 10 10 43.91 7.87 47.18 9.59 −0.357 0.432 −1.265 to 0.551 11.77 11.77
Wachter 2002 4 g/d, 12 w 8 8 17.1 1.6 18.0 1.9 −0.484 0.480 −1.515 to 0.546 9.52 9.52
Total (fixed effects) 83 83 −0.339 0.148 −0.632 to −0.0465 −2.288 0.023 100.00 100.00
Total (random effects) 83 83 −0.339 0.148 −0.632 to −0.0465 −2.288 0.023 100.00 100.00
Authors Carnitine Dosage N1 N2 Mean 1 SD 1 Mean 2 SD 2 SMD SE 95% CI t p Weight (%) Test for Heterogeneity
Fixed Random
Greig 1987 2 g/d, 2 w 9 9 41.4 7.5 41.6 8.8 −0.0233 0.449 −0.975 to 0.928 48.72 49.19 Q 1.5691
Parandak 2014 2 g/d, 2 w 11 10 22.4 0.8 23.0 0.6 −0.809 0.438 −1.724 to 0.107 51.28 50.81 DF 1
Total (fixed effects) 20 20 −0.426 0.313 −1.061 to 0.209 −1.359 0.182 100.0 100.00 Significance level p = 0.2103
Total (random effects) 20 20 −0.422 0.393 −1.218 to 0.373 −1.076 0.289 100.0 100.00 I2 36.27%
95% CI for I2 0.00 to 0.00
Chun 2011 2 g/d, 4 w 6 6 57.07 3.07 57.52 3.42 −0.128 0.533 −1.316 to 1.061 39.25 39.25 Q 0.1393
Greig 1987 2 g/d, 4 w 10 10 45.2 12.0 43.6 12.0 0.128 0.429 −0.773 to 1.028 60.75 60.75 DF 1
Total (fixed effects) 16 16 0.0274 0.334 −0.655 to 0.710 0.0820 0.935 100.0 100.00 Significance level p = 0.7089
Total (random effects) 16 16 0.0274 0.334 −0.655 to 0.710 0.0820 0.935 100.0 100.00 I2 0.00%
95% CI for I2 0.00 to 0.00

VO2: Maximal oxygen consumption, w: weeks, g: grams, d: days, l: milliliter, min: minutes, L-carn: L-carnitine, SD: standard deviation, N: number of subjects, 1: subjects that did not use carnitine, 2: subjects used carn, SMD: standard mean differences, SE: standard error, CI: confidential intervals, SD: standard deviation, I2: inconsistency.