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Behavioral effects of Sox2 ablation in the SCN during the forced swim test. (a) Total bouts of immobility and (b) duration of immobility of Sox2 cKO mice (n = 8) and littermate controls (n = 7) over the course of the forced swim test are presented. Female mice are denoted in pink and male mice are denoted in blue. Outliers are denoted by cross marks. Statistical significance from Wilcoxon rank-sum tests is marked with ** (p < 0.01).
