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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Biol Psychiatry Cogn Neurosci Neuroimaging. 2020 Jul 3;6(7):735–744. doi: 10.1016/j.bpsc.2020.06.015

Figure 1. Study design.

Figure 1.

Ketamine group was administered clinical scales and received an MRI at three time points (T1: pre-treatment/baseline, T2: 24 hours post-first infusion of ketamine, and T3: 24–72 hours post fourth infusion of ketamine). The study length varied from 2–2.5 weeks depending on which day the first infusion started on. Fifty non-depressed healthy controls (HC) received an MRI at baseline (T1) and a subset of the fifty (n=17) HCs received a repeat assessment 2 weeks after T1.