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. Author manuscript; available in PMC: 2021 Nov 29.
Published in final edited form as: J Med Chem. 2020 Oct 7;63(20):12060–12072. doi: 10.1021/acs.jmedchem.0c01394

Table 1.

Binding affinity of compounds 13-15 to mGluR2.

Compound 13 14 15
IC50 ± SEM (nM) 7.6 ± 0.9 10.5 ± 0.5 10.5 ± 7.9
log (IC50 ± SEM) −8.12 ± 0.79 −7.98 ± 0.21 −7.98 ± 1.39