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[Preprint]. 2021 Dec 14:2021.11.23.469747. Originally published 2021 Nov 24. [Version 2] doi: 10.1101/2021.11.23.469747

PMC8629195.1; 2021 Nov 24
PMC8629195.2; 2021 Dec 14

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Figure 2 | — Only those SARS-CoV-2 proteins that affected cell proliferation presented in Figure 1 are shown here. Complete SARS-CoV-2 genome-wide data on fission yeast cellular morphology are included in Fig. S3. (A) shows the effect of individual SARS-CoV-2 proteins on fission yeast cell morphology. Each image was taken 48 h agi using bright field microscopy. Scale bar = 10 μM. (B) Overall cell morphology as shown by the forward scattered analysis. Ten thousand cells were measured 48 h agi. The forward-scatter (FSC) measures the distribution of all cell sizes. The side-scatter (SSC) determines intracellular complexity. Gene-off, no SARS-CoV-2 protein production; gene-on, SARS-CoV-2 protein produced.