Table 2. Spearman correlation coefficients between Λ and µ derived from fitting truncated datasets versus full dataset.

t: days. Note that values of 1.000 are due to only a small number of patients (n = 4) that were imaged before t = 30 days in the validation cohort; these either did not have lesion volumes reassessed before the next reported time threshold (t = 60 days) or did not observe a change in monotonic relationships within this timeframe (t = 30–120 days).

	Calibration cohort					Validation cohort
Λ	t < 60	t < 120	t < 200	t = all days	Λ	t < 60	t < 120	t < 200	t = all days
t < 30	0.476	0.162	0.080	0.071	t < 30	1.000	1.000	0.800	0.800
t < 60		0.416	0.309	0.306	t < 60		0.812	0.658	0.823
t < 120			0.668	0.599	t < 120			0.676	0.750
t < 200				0.730	t < 200				0.771
µ	t < 60	t < 120	t < 200	t = all days	µ	t < 60	t < 120	t < 200	t = all days
t < 30	0.942	0.928	0.922	0.910	t < 30	1.000	0.800	0.800	0.800
t < 60		0.968	0.941	0.946	t < 60		0.974	0.960	0.963
t < 120			0.946	0.922	t < 120			0.971	0.961
t < 200				0.921	t < 200				0.989