Table 2.

Five Tear Observed Progression Free Survival (Kaplan-Meier) and Restricted Mean Survival Time (RMST) According to Minimal Residual Disease Sub-Type

Variable Predictor		% PFS 5 years Kaplan-Meier (95% CI)	Observed RMST 5 years (95% CI)
	I CTC (-) mM (-)	98.1%	4.91 years
	N=105	(87.1-99.7%)	(4.76-5.08)
Prognostic Group
	II CTC (-) mM (+)	62.7%	4.12 years
	N=36	(37.3-80.2%)	(3.55-4.70)
	III CTC (+)	7.0%	1.71 years
	N=40	(0.5-26.2%)	(1.19-2-23)

%, percentage; CI, confidence interval; CTC, circulating tumour cell; mM, micro-metastasis; RMST is the area under the Kaplan-Meier survival curve determined by the