Table 2.

Comparison of plasma amino acid profiles between cirrhosis group, chronic hepatitis B group, and healthy control group ($\overline{X}\pm \text{s}.\text{d}.$).

Amino acid (μmol/L)	Cirrhosis group n = 86	Chronic hepatitis B group n = 80	Healthy control group n = 30	F	P
TAU	428.4 ± 283.3	388.0 ± 37.7	197.5 ± 48.9∗	3.89	0.023
ASP	16.7 ± 11.4	28.5 ± 16.4∗∗	12.9 ± 8.7∗∗	10.00	<0.001
THR	165.6 ± 66.9	178.0 ± 40.4	117.6 ± 19.1∗∗	3.40	0.037
SER	161.8 ± 6.96	152.3 ± 66.5	95.8 ± 25.7∗∗	4.40	0.014
GLU	38.2 ± 12.8	50.9 ± 13.7∗∗	50.3 ± 15.7∗∗	9.44	<0.001
GLY	279.4 ± 105.0	246.5 ± 170.0	184.3 ± 67.2∗	3.34	0.038
ALA	401.4 ± 156.7	397.1 ± 175.1	441.7 ± 189.2	0.296	0.744
GLN	847.1 ± 78.8	733.3 ± 101.7	683.5 ± 98.2∗	2.49	0.046
CYS	106.2 ± 21.8	58.1 ± 11.3∗	63.7 ± 10.1∗	57.64	<0.001
VAL	204.1 ± 94.2	285.0 ± 84.0∗∗	213.3 ± 61.6	5.97	0.003
ILE	92.9 ± 31.2	102.7 ± 31.7	101.6 ± 31.0	0.93	0.396
LEU	135.1 ± 32.9	157.5 ± 37.8∗∗	184.0 ± 18.5∗	18.74	<0.001
TYR	142.4 ± 37.1	82.5 ± 22.6∗∗	58.0 ± 22.4∗∗	44.21	<0.001
PHE	88.3 ± 18.2	62.7 ± 11.1∗∗	45.2 ± 11.9∗∗	42.26	<0.001
HIS	72.6 ± 15.8	72.1 ± 16.3	68.0 ± 13.5	0.37	0.688
TRP	52.4 ± 19.6	44.7 ± 9.3	42.8 ± 6.7	2.40	0.096
ORN	435.8 ± 83.3	439.8 ± 104.4	477.4 ± 96.3	1.00	0.371
LYS	215.1 ± 55.1	204.3 ± 45.3	180.8 ± 35.8	2.06	0.132
ARG	88.1 ± 23.2	76.5 ± 15.5∗	72.2 ± 16.5∗	4.05	0.020
PRO	189.5 ± 42.6	186.6 ± 41.1	194.3 ± 34.7	0.11	0.897
MET	27.3 ± 5.4	18.9 ± 4.7∗∗	21.5 ± 5.1∗∗	7.25	0.007
BCAA/AAA	1.59 ± 0.52	2.98 ± 0.62∗	3.41 ± 0.68∗	83.91	<0.001

Abbreviations: TAU: taurine; ASP: aspartic acid; THR: threonine; SER: serine; GLU: glutamic acid; GLY: glycine; ALA: alanine; GLN: glutamine; CYS: cysteine; VAL: valine; LEU: leucine; ILE: isoleucinetyrosine; TYR: tyrosine; PHE: phenylalanine; HIS: histidine; TRP: tryptophan; ORN: ornithine; LYS: lysine; ARG: arginine; PRO: proline; MET: methionine. ^∗P < 0.05 compared with cirrhosis group; ^∗∗P < 0.01 compared with cirrhosis group.