Bao 2021.

Methods	Study design: RCT Setting: China
Participants	66 CD patients
Interventions	IG: acupuncture with moxibustion CG: sham‐acupuncture with sham‐moxibustion
Outcomes	The score of the hospital anxiety‐depression scale (HADS) and the score of intestinal core symptoms (degree of abdominal pain and frequency of diarrhea) were observed in the patients of the two groups. The concentration of plasma indoleamine 2,3‐dioxygenase 1 (IDO1) and the ratios of Kyn/Trp, QuinA/Kyn, KynA/Kyn and KynA/QuinA were compared between the two groups.
Notes	This study was identified on our updated search and will be included in the next update of this review