| Study name |
Association between functional changes in the brain and the perception of pain in patients with inflammatory bowel diseases (IBD) ‐ measured with functional magnetic resonance imaging |
| Methods |
RCT |
| Participants |
84 adults 18 to 80 years old |
| Interventions |
IG: transcranial direct current stimulation
CG: sham transcranial direct current stimulation |
| Outcomes |
Primary outcome measures:
Functional and/or structural changes in the brain measured with cerebral MRI [ Time Frame: 2 week ] Participants will be followed for 2 weeks. Changes in pain measured with VAS [ Time Frame: 2 weeks ] Participants will be followed for 2 weeks. Changes in perception of pain measured with an algometer (pain pressure threshold) [ Time Frame: 2 weeks ] Participants will be followed for 2 weeks.
Secondary outcome measures:
Changes in questionnaire "quality of life" [ Time Frame: 2 weeks ] questionnaire Changes in functional symptoms [ Time Frame: 2 weeks ] Questionnaire: IBS‐SSS Changes in activity indices [ Time Frame: 2 weeks ] HBI or SCCAI Changes in pain catastrophising scale [ Time Frame: 2 weeks ] Changes in inflammation biomarker (blood ‐ CRP) [ Time Frame: 2 weeks ] Changes in inflammation biomarker (stool ‐ calprotectin) [ Time Frame: 2 weeks ]
|
| Starting date |
24 January 2017 |
| Contact information |
magdalena.pruess@charite.de |
| Notes |
Sponsor: Charite University, Berlin, Germany |
