Table 3. CAVI value according to the category for LDL-C management proposed by JAS Guidelines 2017.
| Males | Females | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total | Management classification | Total | Management classification | |||||||||
| Category I | Category II | Category III | p for trend | Category I | Category II | Category III | p for trend | |||||
| (A) | ||||||||||||
| Number of participants, n | 909 | 117 | 360 | 432 | 1,063 | 392 | 290 | 381 | ||||
| Mean CAVI value (±SD) | 8.6±1.1 | 7.7±1.0 | 8.5±1.1 | 8.9±1.1 | ＜0.001 | 8.1±1.0 | 7.7±0.9 | 8.4±0.9 | 8.3±1.0 | ＜0.001 | ||
| CAVI ≥ 9.0, % | 34.8 | 12.0 | 28.3 | 46.3 | ＜0.001 | 18.3 | 8.4 | 25.9 | 22.6 | ＜0.001 | ||
| Crude OR (95% CI) | 1.0 | 2.91 | 6.34 | 1.0 | 3.79 | 3.17 | ||||||
| (1.59 - 5.31) | (3.52 - 11.4) | (2.44 - 5.91) | (2.06 - 4.87) | |||||||||
| Multivariable OR (95% CI) § | 1.0 | 2.96 | 7.33 | 1.0 | 3.99 | 3.34 | ||||||
| (1.61 - 5.43) | (4.03 - 13.3) | (2.55 - 6.24) | (2.16 - 5.16) | |||||||||
|
III (excluding DM, CKD, or PAD) |
DM, CKD, or PAD |
p for difference |
III (excluding DM, CKD, or PAD) |
DM, CKD, or PAD |
p for difference | |||||||
| (B) | ||||||||||||
| Number of participants, n | 68 | 364 | 7 | 374 | ||||||||
| Mean CAVI value (±SD) | 9.1±0.9 | 8.8±1.1 | 0.11 | 8.4±0.4 | 8.3±1.0 | 0.74 | ||||||
| CAVI ≥ 9.0, % | 55.9 | 44.5 | 0.062 | 0 | 23.0 | 0.11 | ||||||
| Crude OR (95% CI) | 1.0 | 2.91 | 9.31 | 5.90 | 1.0 | 3.80 | - | 3.25 | ||||
| (1.59 - 5.31) | (4.46 - 19.4) | (3.25 - 10.7) | (2.44 - 5.91) | (2.11 - 5.00) | ||||||||
| Multivariable OR (95% CI) § | 1.0 | 2.96 | 10.3 | 6.85 | 1.0 | 3.99 | - | 3.41 | ||||
| (1.61 - 5.43) | (4.88 - 21.6) | (3.74 - 12.6) | (2.55 - 6.24) | (2.20 - 5.27) | ||||||||
| III (excluding DM) | DM | p for difference | III (excluding DM) | DM | p for difference | |||||||
| (C) | ||||||||||||
| Number of participants, n | 253 | 179 | 302 | 79 | ||||||||
| Mean CAVI value (±SD) | 8.8±1.0 | 8.9±1.1 | 0.40 | 8.2±1.0 | 8.4±1.0 | 0.090 | ||||||
| CAVI ≥ 9.0, % | 44.7 | 48.6 | 0.38 | 20.5 | 30.4 | 0.040 | ||||||
| Crude OR (95% CI) | 1.0 | 2.91 | 5.93 | 6.95 | 1.0 | 3.79 | 2.81 | 4.75 | ||||
| (1.59 - 5.31) | (3.22 - 10.9) | (3.70 - 13.1) | (2.44 - 5.91) | (1.79 - 4.42) | (2.61 - 8.63) | |||||||
| Multivariable OR (95% CI) § | 1.0 | 2.96 | 6.54 | 8.83 | 1.0 | 4.03 | 2.92 | 5.56 | ||||
| (1.62 - 5.44) | (3.53 - 12.1) | (4.62 - 16.9) | (2.57 - 6.30) | (1.85 - 4.61) | (3.00 - 10.3) | |||||||
| III (excluding CKD) | CKD | p for difference | III (excluding CKD) | CKD | p for difference | |||||||
| (D) | ||||||||||||
| Number of participants, n | 198 | 234 | 66 | 315 | ||||||||
| Mean CAVI value (±SD) | 8.9±1.1 | 8.9±1.1 | 0.77 | 8.2±0.9 | 8.3±1.0 | 0.75 | ||||||
| CAVI ≥ 9.0, % | 47.5 | 45.3 | 0.63 | 18.2 | 23.5 | 0.30 | ||||||
| Crude OR (95% CI) | 1.0 | 2.91 | 6.65 | 6.09 | 1.0 | 3.79 | 2.42 | 3.34 | ||||
| (1.59 - 5.31) | (3.56 - 12.4) | (3.29 - 11.3) | (2.44 - 5.91) | (1.18 - 5.00) | (2.15 - 5.19) | |||||||
| Multivariable OR (95% CI) § | 1.0 | 2.96 | 7.81 | 6.96 | 1.0 | 3.98 | 2.77 | 3.45 | ||||
| (1.61 - 5.43) | (4.14 - 14.7) | (3.73 - 13.0) | (2.55 - 6.23) | (1.33 - 5.76) | (2.20 - 5.39) | |||||||
| III (excluding PAD) | PAD | p for difference | III (excluding PAD) | PAD | p for difference | |||||||
| (E) | ||||||||||||
| Number of participants, n | 424 | 8 | 377 | 4 | ||||||||
| Mean CAVI value (±SD) | 8.9±1.1 | 8.2±0.9 | 0.089 | 8.3±1.0 | 7.2±1.3 | 0.019 | ||||||
| CAVI ≥ 9.0, % | 46.5 | 37.5 | 0.59 | 22.8 | 0 | 0.23 | ||||||
| Crude OR (95% CI) | 1.0 | 2.91 | 6.38 | 4.41 | 1.0 | 3.80 | 3.22 | - | ||||
| (1.59 - 5.31) | (3.54 - 11.5) | (0.95 - 20.5) | (2.44 - 5.91) | (2.09 - 4.94) | ||||||||
| Multivariable OR (95% CI) § | 1.0 | 2.96 | 7.43 | 4.05 | 1.0 | 3.99 | 3.38 | - | ||||
| (1.61 - 5.43) | (4.08 - 13.5) | (0.86 - 19.2) | (2.55 - 6.25) | (2.19 - 5.23) | ||||||||
§ Adjusted for body mass index (continuous) and drinking habit (current or not).