Table 1. Baseline characteristics and angiographic features.
| Variables | sST2 ≤ 34.2 ng/ml ( n = 157) | sST2 ＞ 34.2 ng/ml ( n = 48) | P value |
|---|---|---|---|
| Age, years, mean±SD | 61.13±9.67 | 63.71±10.02 | 0.111 |
| Male, n (%) | 106 (67.5) | 37 (77.1) | 0.207 |
| Hypertension, n (%) | 65 (41.4) | 22 (45.8) | 0.587 |
| Diabetes mellitus, n (%) | 104 (66.2) | 35 (72.9) | 0.386 |
| Smoking, n (%) | 74 (47.1) | 18 (37.5) | 0.24 |
| History of stroke/TIA, n (%) | 14 (8.9%) | 5 (10.4) | 0.778 |
| SBP, mmHg, mean±SD | 132.18±18.49 | 137.08±18.49 | 0.129 |
| DBP, mmHg, mean±SD | 80.37±11.23 | 80.35±11.65 | 0.993 |
| HR, beats/min, mean±SD | 68.81±10.49 | 71.98±12.19 | 0.08 |
| Creatinine, µmol/L, mean±SD | 70.14±17.16 | 77.06±17.16 | 0.287 |
| eGFR, ml/min/1.73 m 2 , mean±SD | 96.31±21.39 | 86.77±18.26 | 0.006 |
| TC, mmol/L, mean±SD | 3.89±1.02 | 4.31±1.05 | 0.014 |
| LDL-C, mmol/L, mean±SD | 2.36±0.89 | 2.63±0.95 | 0.07 |
| HDL-C, mmol/L, mean±SD | 0.94±0.23 | 1.03±0.35 | 0.092 |
| WBC counts, ×10 9 /L, mean±SD | 6.31±1.72 | 7.33±2.29 | 0.006 |
| Neutrophil counts, ×10 9 /L, mean±SD | 3.9±2.96 | 3.3±2.23 | 0.211 |
| Platelet counts, ×10 9 /L, mean±SD | 195.75±45.73 | 195.25±42.65 | 0.946 |
| Peak cTnI, µg/L, mean±SD | 0.093 (0.035-0.57) | 0.7 (0.115-4.08) | ＜0.001 |
| NT-pro BNP, pg/mL, mean±SD | 104.2 (46.4-388.7) | 400.4 (132.8-848.2) | ＜0.001 |
| LVEF, %, mean±SD | 62.18±5.53 | 60.5±4.93 | 0.066 |
| Medications, n (%) | |||
| Ticagrelor | 84 (53.5) | 28 (58.3) | 0.556 |
| Clopidogrel | 73 (46.5) | 20 (41.7) | 0.556 |
| Beta blocker | 148 (94.3) | 46 (95.8) | 0.665 |
| ACEI/ARB | 144 (91.7) | 45 (93.8) | 0.639 |
| Nicorandil | 69 (43.9) | 21 (43.8) | 0.981 |
| Statin | 157 (100) | 48 (100) | 1 |
| sST2, ng/mL, mean±SD | 19.7 (13.68-26.4) | 42.8 (36.02-52.7) | ＜0.001 |
| Multivessel disease, n (%) | 102 (65) | 42 (87.5) | 0.002 |
| Initial TIMI flow grade, n (%) | ＜0.001 | ||
| 0-1 | 13 (8.3) | 11 (22.9) | |
| ≥ 2 | 144 (91.7) | 37 (77.1) | |
| Multistent, n (%) | 82 (52.2%) | 35 (72.9) | 0.01 |
| Gensini Score | 34.7±25.09 | 53.67±24.44 | ＜0.001 |
| No-reflow phenomenon, n (%) | 11 (7) | 10 (20.8) | 0.012 |
Abbreviations: eGFR, estimated glomerular filtration rate; TIA, transient ischemic attack; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; cTnI, cardiac troponin I; NT-pro BNP, N-terminal pro-B-type natriuretic peptide; LVEF, left ventricular ejection fraction; ACEI: angiotensin-converting enzyme inhibitors; ARB: angiotensin receptor blockers; sST2: soluble suppression of tumorigenicity 2; WBC:white blood cell; SD, standard deviation