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. 2021 Aug 2;23(12):2369–2377. doi: 10.1038/s41436-021-01285-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Urinary desoxypyridinoline/creatinine ratio (Dpd/Crea) from patients with MLII, MLIII alpha/beta, and MLIII gamma, as well as from control individuals in relation to the age-matched reference range (gray boxes) [28, 29]. Of note, due to the premature death of patients with MLII and MLIII alpha/beta those patients are not present in all cohorts.