. Author manuscript; available in PMC: 2022 Nov 1.

Published in final edited form as: J Abnorm Psychol. 2021 Oct 7;130(8):829–840. doi: 10.1037/abn0000716

Table 1.

Age Moderating T1 Inflammatory Activity Predicting T1-T2 Change in MDD Status

	Younger	Older
	β (SE)	β (SE)
Factor Loadings
T1 Latent Inflammatory Activity
T1 Log IL-6 Level	0.482	0.591
T1 Log CRP Level	0.833^***(0.234)	0.813^***(0.278)
T1 Log Fibrinogen Level	0.659^***(0.037)	0.504^***(0.040)
ΔMDD Status	0.482	0.838

Regression Slopes
T1 MDD Status → T1-T2 ΔMDD Status	−0.467^***(0.101)	−0.833^***(0.071)
T1 Inflammatory Activity → T1-T2 ΔMDD Status	0.085^*(0.041)	0.063 (0.035)

Model Fit Indices
χ²	43.396
df	12
p	< .001
CFI	.940
RMSEA	.075

Note.

p < .05;

^***

p < .001.

β = unstandardized regression weight or standardized factor loading; Δ = change across T1 and T2; CFI = confirmatory factor index; CRP = C-reactive protein; IL-6 = interleukin-6; df= degrees of freedom; MDD = major depressive disorder; RMSEA = root mean square error of approximation; SE = standard error; T1 = time 1; T2 = time 2.