TABLE 1.

Characteristics of enrolled non-sepsis volunteers and sepsis patients at sepsis recognition (T0). Clinical parameters, cytokine levels in the plasma, and supernatant following LPS stimulation (10 ng/mL) of PBMCs

	Nonsepsis control (n = 2)		Sepsis nonsurvivor (n = 2)		Sepsis survivor (n = 3)
Gender	Male	Female	Male	Female	Male	Female	Female
Age range	35-40	45-50	90-95	65-70	45-50	65-70	70-75
Sepsis etiology	n/a	n/a	E.coli bacteremia			E.coli bacteremia
APACHEII	n/a	n/a	18	38	31	41	19
SOFA	n/a	n/a	11	16	11	15	7
Time of death (days post enrollment)	n/a	n/a	<30	1	n/a	n/a	n/a
Plasma cytokines (ng/mL)
Resistin	22.5	36.7	202	135.9	147	281	92
IL-6	N.D	0.002	30.2	142.3	133	2.48	0.31
IL-8	0.03	0.026	6.65	27.2	41.7	0.61	0.4
IL-10	N.D.	N.D.	0.13	9.71	0.52	0.15	0.39
LPS-induced TNFα (ng/mL)
TNF-α	0.656	0.979	0.45	0.0046	n/a	0.047	0.1

Abbreviations: APACHE II, acute physiology and chronic health evaluation II; SOFA, sequential organ failure assessment; N.D., Not detected; n/a, not applicable.