Table 3.
Effect of Advanced Dental Cleaning on Primary Outcomes (Poisson Regression)
| Baseline Variables | Adjusted Analyses | p-value | Adjusted Analyses | p-value |
|---|---|---|---|---|
| Total Population | Population Attending 6-Month Follow-Up | |||
| Regression Coefficient (95% CI) | Regression Coefficient (95% CI) | |||
| Randomization group | ||||
| Intervention | 0.36 (0.25 to 0.52) | <0.0001 | 0.16 (0.10 to 0.27) | <0.0001 |
| Control | Ref | Ref | ||
| Sex | ||||
| Male | Ref | <0.0001 | Ref | <0.0001 |
| Female | 0.32 (0.23 to 0.45) | 0.32 (0.21 to 0.47) | ||
| Age | 0.97 (0.95 to 0.98) | <0.0001 | 0.98 (0.97 to 1.00) | 0.061 |
| Current daily smoking | 0.56 (0.37 to 0.88) | 0.011 | 0.41 (0.23 to 0.71) | 0.002 |
| CAT score | 1.07 (1.04 to 1.09) | <0.0001 | 1.06 (1.03 to 1.10) | <0.0001 |
| Exacerbation frequency | 1.11 (1.04 to 1.17) | 0.001 | 1.25 (1.14 to 1.36) | <0.0001 |
| FEV1%pred | 1.01 (1.00 to 1.02) | 0.283 | 1.02 (1.01 to 1.03) | 0.002 |
Notes: Association of intervention with exacerbations frequency during the study period, compared with the control group, assessed by Poisson regression analysis with adjustment for sex, age, current daily smoking, CAT score, exacerbation frequency previous 12 months, and FEV1%pred at baseline. The model was repeated both in the total population and in the population attending the 6-month follow-up with repeated intervention.
Abbreviations: CAT, COPD Assessment Test; CI, confidence interval; FEV1%pred, Forced expiratory volume in one second in percentage of predicted value.