Table 2.
Linear regression of the mean difference (β (95% CI)) in late-life cognitive test z-score by composite socioeconomic and cardiovascular risk factors
| Executive Function | Verbal Episodic Memory | Semantic Memory | |||||||
|---|---|---|---|---|---|---|---|---|---|
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| Models* | Model 1† | Model 2‡ | Model 3§ | Model 1† | Model 2‡ | Model 3§ | Model 1† | Model 2‡ | Model 3§ |
| Born in Stroke Belt (ref: Born Elsewhere) | −0.16 (−0.35, 0.04) | −0.08 (−0.28, 0.12) | −0.05 (−0.25, 0.14) | −0.06 (−0.26, 0.15) | 0.03 (−0.18, 0.24) | 0.03 (−0.18, 0.24) | −0.36 (−0.56, −0.16) | −0.30 (−0.51, −0.09) | −0.28 (−0.49, −0.07) |
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| Socioeconomic Composite (ref: 0 Risk Factors) | |||||||||
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| 1 Risk Factor | −0.37 (−0.60, −0.14) | −0.45 (−0.68, −0.22) | −0.33 (−0.57, −0.09) | −0.37 (−0.62, −0.13) | −0.48(−0.72, −0.24) | −0.49 (−0.74, −0.24) | |||
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| 2+ Risk Factors | −0.66 (−0.91, −0.41) | −0.72 (−0.97, −0.48) | −0.36 (−0.62, −0.09) | −0.38 (−0.65, −0.11) | −0.63 (−0.89, −0.37) | −0.61 (−0.87, −0.34) | |||
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| Cardiovascular Composite (ref: 0 Risk Factors) | |||||||||
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| 1 Risk Factor | −0.04 (−0.22, 0.14) | −0.04 (−0.22, 0.14) | 0.03 (−0.16, 0.21) | 0.00 (−0.19, 0.19) | −0.02 (−0.21, 0.17) | −0.02 (−0.21, 0.17) | |||
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| 2+ Risk Factors | −0.27 (−0.47, −0.06) | −0.26 (−0.46, −0.05) | −0.26 (−0.48, −0.04) | −0.25 (−0.47, −0.03) | −0.26 (−0.48, −0.04) | −0.24 (−0.45, −0.02) | |||
*
All models adjusted for birth year, gender, and parental education
†
Model 1 adjusted for SES composite
‡
Model 2 adjusted for CVRF composite
§
Model 3 adjusted for SES composite and CVRF composite