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. 2021 Nov 29;11:23070. doi: 10.1038/s41598-021-02106-4

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Linkage disequilibrium encompassing the HLA-G and HLA-A region, considering 5347 individuals from worldwide population samples and SNPs with minimum allele frequency higher than 1%. We have removed variants that coincides with known structural variants, producing three continuous segments: chr6:29,823,675–29,874,064, starting from the HLA-G promoter up to 43 Kb downstream HLA-G, chr6:29,881,527–29,883,079, a 1.5 kb region between HLA-A and HLA-G, and chr6:29,938,412–29,945,862, starting 4 kb upstream HLA-A to the end of the HLA-A 3’UTR.