Table 1.
Resources available for download or listed as supplementary material regarding the HLA-G gene and its polymorphisms.
| Resource | Description | Availability |
|---|---|---|
| VCF listing all variants | A VCF file containing all variants, the reference and alternative alleles, and global counts, to be used as support for variant refinement when genotyping HLA-G in NGS procedures or variant annotation | For downloada |
| Phased VCF | A VCF file with the phased genotypes for each sample | Upon request |
| FASTA file with full sequences | A copy of every full-length sequence observed in this survey (approximately 12 Kb each), and their global counts | For downloada |
| FASTA file with gene sequences | The full sequence of each HLA-G allele (exons + introns) observed in this survey, with their global counts. Each sequence is identified with its official name according to the IPD-IMGT/HLA database, or as a novel sequence | For downloada |
| FASTA file with CDS sequences | We extracted all different exonic sequences (CDS). This file contains a copy of each different sequence, with their global counts. Each sequence is identified with its official name according to the IPD-IMGT/HLA database, or as a novel sequence | For downloada |
| FASTA file with protein sequences | We translated all exonic sequences into proteins (allotypes). This file contains a copy of each different sequence, with their global counts. Each sequence is identified with its official name according to the IPD-IMGT/HLA database, or as a novel sequence | For downloada |
| FASTA file with 3’UTR sequences | The sequence of each 3’UTR haplotype we have detected, with their names and global counts | For downloada |
| SNP frequencies | This table provides the frequency for the reference and alternative alleles in the global population, in XLSX format | Supplementary material (Table S2) |
| Genomic alleles (4-digit resolution) frequencies | This table provides the frequency for each genomic allele (4-digit resolution) in each population we have studied, in XLSX format. There are 3 sheets, one for biogeographic regions, one for countries, and one for specific population samples | Supplementary material (Table S3) |
| Allotypes frequencies (2-digit resolution) | This table provides the frequency for each allotype (2-digit resolution, full-length protein) in each population we have studied, in XLSX format. There are 3 sheets, one for biogeographic regions, one for countries, and one for specific population samples | Supplementary material (Table S4) |
| 3’UTR frequencies | This table provides the frequency for 3’UTR haplotype in each population we have studied, in XLSX format. There are 4 sheets, one for biogeographic regions, one for countries, one for specific population samples, and one describing the combination between genomic alleles and 3’UTR haplotypes in the global sample | Supplementary material (Table S5) |
aAvailable for download in www.castelli-lab.net/HLA-G.