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. 2021 Nov 29;11:23070. doi: 10.1038/s41598-021-02106-4

Table 4.

The relationship between HLA-G alleles and 3’UTR haplotypes, for combinations that have occurred at least twice in 4640 individuals across the globe.

HLA-G allele 3'UTR haplotype Global frequencya Internal frequencyb
G*01:01:01:01 UTR-06 0.0027 0.0116
G*01:01:01:01 UTR-60 0.0002 0.0009
G*01:01:01:01 UTR-01 0.2277 0.9846
G*01:01:01:04 UTR-20 0.0036 0.1000
G*01:01:01:04 UTR-18 0.0198 0.5576
G*01:01:01:04 UTR-06 0.0121 0.3394
G*01:01:01:05 UTR-04 0.0704 0.9985
G*01:01:01:06 UTR-27 0.0002 0.0161
G*01:01:01:06 UTR-04 0.0131 0.9839
G*01:01:01:08 UTR-01 0.0204 1.0000
G*01:01:01:09 UTR-01 0.0033 1.0000
G*01:01:01:13 UTR-06 0.0066 1.0000
G*01:01:01:14Q UTR-01 0.0004 1.0000
G*01:01:02:01 UTR-02 0.1470 0.9956
G*01:01:02:01 UTR-10 0.0002 0.0015
G*01:01:02:02 UTR-02 0.0045 1.0000
G*01:01:02:04 UTR-02 0.0015 1.0000
G*01:01:03:03 UTR-07 0.0744 0.9957
G*01:01:03:03 UTR-31 0.0002 0.0029
G*01:01:03:04 UTR-07 0.0002 1.0000
G*01:01:12 UTR-02 0.0022 1.0000
G*01:01:14 UTR-02 0.0025 1.0000
G*01:01:15 UTR-06 0.0039 1.0000
G*01:01:17 UTR-02 0.0026 1.0000
G*01:01:19 UTR-02 0.0017 1.0000
G*01:01:22:01 UTR-02 0.0128 1.0000
G*01:01:22:04 UTR-02 0.0004 1.0000
G*01:03:01:02 UTR-56 0.0029 0.0510
G*01:03:01:02 UTR-17 0.0038 0.0662
G*01:03:01:02 UTR-48 0.0004 0.0076
G*01:03:01:02 UTR-05 0.0499 0.8752
G*01:04:01:01 UTR-03 0.1211 0.9799
G*01:04:01:01 UTR-02 0.0004 0.0035
G*01:04:01:01 UTR-13 0.0018 0.0148
G*01:04:01:02 UTR-53 0.0002 0.0227
G*01:04:01:02 UTR-03 0.0093 0.9773
G*01:04:04 UTR-23 0.0009 0.0171
G*01:04:04 UTR-03 0.0495 0.9829
G*01:04:05 UTR-03 0.0027 1.0000
G*01:05 N UTR-02 0.0243 1.0000
G*01:06:01:01 UTR-02 0.0484 1.0000
G*01:06:01:02 UTR-02 0.0009 1.0000
G*01:08:02 UTR-02 0.0003 1.0000
G*01:11 UTR-03 0.0009 1.0000
G*01:14 UTR-05 0.0006 1.0000
G*01:21 N UTR-03 0.0002 1.0000
G*01:26 UTR-02 0.0002 1.0000

aThe global frequency of this haplotype.

bConsidering all the 3’UTR haplotypes associated with a given genomic allele, this is the frequency in which this specific 3’UTR haplotype follows the given genomic allele. An internal frequency of 1.000 indicates that the given genomic allele always presents the same 3’UTR sequence.