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. 2021 Nov 29;12:6947. doi: 10.1038/s41467-021-27222-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Test server setup with the web browser as the user interface, the frontend in bright green, and the backend in light green. The code is stored in GitHub, shown in dark gray. B Specific goals for our scientific tests, driven by flaws in a previous iteration of these tests. Each point is described in detail in the text. C Basic infrastructure of the scientific test framework, motivated by simplicity. Each box represents a file, folder, or script that is either provided in the template folder or generated throughout the protocol run. The basic workflow is highlighted in green with components that facilitate documentation and maintenance shown in white. [Icons in Fig. 1B were created by Ana Teixeira, Aman, Ben Davis, Gregor Cresnar, Anna Sophie, and Joel Avery from Noun Project.] SQL structured query language, HPC cluster high-performance computing cluster.