Table 1.
The table represents a list of compounds tested in ERα activation.
| Compound | Provider | Mode of Action | Concentration |
|---|---|---|---|
| 17β-estradiol | Sigma-Aldrich/Merck | 0.1–10 nM | |
| IGF-1 | Sigma-Aldrich/Merck | 5 ng/ml | |
| Ryanodine | Tocris Bioscience | Ca2+ release inhibitor | 100–100 mM |
| BAPTA-Am | Abcam (ab120503) | Cell permeant Ca2+ chelator | 1–10 mM |
| MK-2206 | ChemieTek | AKT inhibitor | 10 nM |
| MK-0752 | Selleckchem | Gamma secretase /notch inhibitor | 5–10 nM |
| Pictilisib | LC Laboratories | PI3K inhibitor, pan-class I B kinase inhibitor | 10 nM |
| Prolactin | Biotechne | 100 ng/ml | |
| GSK-343 | Sigma-Aldrich/Merck | EZH2 inhibitor | 100–3 mM |
| Estriol | Sigma-Aldrich/Merck | 100 mM | |
| Dantrolene | Santa Cruz | Ca2+ release inhibitor | 50 mM |
| SP600125 | Sellechem | inhibitor | 10 μM |
| RWJ67657 | Sellechem | p38 inhibitor | 10 μM |
| SB203580 | Sellechem | p38 inhibitor | 20 μM |