TABLE 2.
Sociodemographic characteristics by prenatal versus pediatric consent for exome sequencing
| Prenatal (N = 289) | Pediatric (N = 393) | p value | |
|---|---|---|---|
| Median maternal age at enrollment (IQR)-weeks | 32 (29–35) | 34 (28–41) | 0.003 |
| Median paternal age at enrollment (IQR)-weeks | 34 (31–38) | 37 (31–44) | <0.001 |
| Maternal race/ethnicity | <0.001 | ||
| American Indian/Alaska Native | 0 (0.0) | 3 (0.8) | |
| Asian | 43 (14.9) | 37 (9.4) | |
| Native Hawaiian/Pacific islander | 1 (0.3) | 5 (1.3) | |
| Non-hispanic Black | 6 (2.1) | 17 (4.3) | |
| Non-hispanic White | 125 (43.3) | 82 (20.9) | |
| Hispanic or Latina | 49 (16.9) | 178 (45.3) | |
| Unknown | 46 (15.9) | 46 (11.7) | |
| Multiracial | 19 (6.6) | 25 (6.4) | |
| Paternal race/ethnicity | <0.001 | ||
| American indian/Alaska Native | 1 (0.3) | 4 (1.0) | |
| Asian | 41 (14.2) | 29 (7.4) | |
| Native Hawaiian/Pacific islander | 0 (0.0) | 5 (1.3) | |
| Non-hispanic Black | 7 (2.4) | 21 (5.3) | |
| Non-hispanic White | 122 (42.2) | 84 (21.4) | |
| Hispanic or Latino | 47 (16.3) | 156 (39.7) | |
| Unknown | 68 (23.5) | 78 (19.8) | |
| Multiracial | 3 (1.0) | 16 (4.1) | |
| Highest level of maternal education | <0.001 | ||
| Less than high school | 5 (1.7) | 90 (22.9) | |
| High school diploma or equivalent | 24 (8.3) | 89 (22.6) | |
| Some college or Associate’s degree | 43 (14.9) | 91 (23.2) | |
| Bachelor’s degree | 65 (22.5) | 41 (10.4) | |
| Professional or graduate degree | 61 (21.1) | 27 (6.9) | |
| Unknown | 91 (31.5) | 55 (14.0) | |
| Highest level of paternal education | <0.001 | ||
| Less than high school | 12 (4.2) | 61 (15.5) | |
| High school diploma or equivalent | 33 (11.4) | 72 (18.3) | |
| Some college or Associate’s degree | 37 (12.8) | 53 (13.5) | |
| Bachelor’s degree | 61 (21.1) | 30 (7.6) | |
| Professional or graduate degree | 44 (15.2) | 19 (4.8) | |
| Unknown | 102 (35.3) | 158 (40.2) | |
| Maternal relationship status | <0.001 | ||
| Single | 12 (4.2) | 46 (11.7) | |
| Married | 185 (64.0) | 196 (49.9) | |
| In a relationship | 48 (16.7) | 80 (20.4) | |
| Divorced or separated | 0 (0.0) | 19 (4.8) | |
| Widowed | 0 (0.0) | 4 (1.0) | |
| Unknown | 44 (15.2) | 48 (12.2) | |
| Use of interpreter | 27 (9.3) | 155 (39.4) | <0.001 |
Note: Proportions presented as N (%). Continuous variables presented as median (IQR).
Abbreviation: IQR, interquartile range.