TABLE 3.
Sociodemographic characteristics by acceptance of secondary findings
| Accepted secondary findings (N = 576) | Declined secondary findings (N = 106) | p-value | |
|---|---|---|---|
| Prenatal | 249 (43.2) | 40 (37.7) | 0.3 |
| Median maternal age at enrollment (IQR)-weeks | 33 (29–37) | 34 (30–37) | 0.59 |
| Median paternal age at enrollment (IQR)-weeks | 35 (31–40) | 35.5 (31–39) | 0.88 |
| Maternal race/ethnicity | 0.72 | ||
| American Indian/Alaska Native | 3 (0.5) | 0 (0.0) | |
| Asian | 64 (11.1) | 16 (15.0) | |
| Native Hawaiian/Pacific islander | 5 (0.9) | 1 (0.9) | |
| Non-hispanic Black | 22 (3.8) | 1 (0.9) | |
| Non-hispanic White | 176 (30.6) | 31 (29.2) | |
| Hispanic or Latina | 189 (32.8) | 38 (35.8) | |
| Unknown | 79 (13.7) | 13 (12.2) | |
| Multiracial | 38 (6.6) | 6 (5.7) | |
| Paternal race/ethnicity | 0.45 | ||
| American Indian/Alaska Native | 5 (0.9) | 0 (0.0) | |
| Asian | 56 (9.7) | 14 (13.2) | |
| Native Hawaiian/Pacific islander | 4 (0.7) | 1 (0.9) | |
| Non-hispanic Black | 27 (4.7) | 1 (0.9) | |
| Non-hispanic White | 172 (29.9) | 34 (32.1) | |
| Hispanic or Latino | 168 (29.2) | 35 (33.0) | |
| Unknown | 127 (22.0) | 19 (17.9) | |
| Multiracial | 17 (2.9) | 2 (1.9) | |
| Highest level of maternal education | 0.64 | ||
| Less than high school | 79 (13.7) | 16 (15.1) | |
| High school diploma or equivalent | 96 (16.7) | 17 (16.0) | |
| Some college or Associate’s degree | 115 (20.0) | 19 (17.9) | |
| Bachelor’s degree | 92 (16.0) | 14 (13.2) | |
| Professional or graduate degree | 69 (12.0) | 19 (17.9) | |
| Unknown | 125 (21.7) | 21 (19.8) | |
| Highest level of paternal education | 0.92 | ||
| Less than high school | 60 (10.4) | 13 (12.2) | |
| High school diploma or equivalent | 90 (15.6) | 15 (14.2) | |
| Some college or Associate’s degree | 75 (13.0) | 15 (14.2) | |
| Bachelor’s degree | 77 (13.4) | 14 (13.2) | |
| Professional or graduate degree | 51 (8.9) | 12 (11.3) | |
| Unknown | 223 (38.7) | 37 (35.9) | |
| Maternal relationship status | 0.41 | ||
| Single | 47 (8.2) | 11 (10.4) | |
| Married | 319 (55.4) | 62 (58.5) | |
| In a relationship | 108 (18.8) | 20 (18.9) | |
| Divorced or separated | 19 (3.3) | 0 (0.0) | |
| Widowed | 4 (0.8) | 0 (0.0) | |
| Unknown | 79 (13.7) | 13 (12.2) | |
| Use of interpreter | 152 (26.4) | 30 (28.3) | 0.68 |
| Termination or stillbirth of probanda | 120 (48.4) | 14 (35.0) | 0.12 |
Note: Proportions presented as N (%). Continuous variables presented as median (interquartile range).
Abbreviation: IQR, interquartile range.
a
Only prenatal subjects included, N = 288