. 2021 Nov 29;11:23080. doi: 10.1038/s41598-021-01660-1

Box 1.

Concentrations of biomarkers as a function of membrane pore size (Dp), Qb, and t.

$C 5 a [p g / m L] = 62887.95 - 808.46 \cdot Dp [nm] + 102.68 \cdot Qb [mL / min] - 304.16 \cdot t [min]$	(1)
$P r o p e r d i n [p g / m L] = 1.12 E^{7} + 7680.83 \cdot Qb [mL / min] - 42987.50 \cdot t [min] + 713.90 \cdot Qb [mL / min] \cdot t [min]$	(2)
$C 5 b 9 [pg / mL] = 1553.94 + 36.04 \cdot Dp [nm] - 1.80 \cdot Qb - 18.27 \cdot t [min] + 1.41 \cdot Dp [nm] \cdot Qb [mL / min] + 0.22 \cdot Qb [mL / min] \cdot t [min]$	(3)
$Serpin [pg / mL] = 1.59 E^{8} + 4.58 E^{5} \cdot Qb [mL / min] - 1.78 E^{6} \cdot t [min] - 17722.047 \cdot Qb [mL / min] \cdot t [min]$	(4)
$I L 1 β [pg / mL] = 2.84 - 0.0066 \cdot Dp [nm] - 0.00082 \cdot Qb - 0.0095 \cdot t [min] + 0.000052 \cdot Qb \cdot t [min]$	(5)
$I L 1 α [pg / mL] = 1.36 - 0.0024 \cdot Dp [nm] - 0.0017 \cdot Qb [mL / min] + 0.039 \cdot t [min] - 0.0024 \cdot Dp \cdot t [min] - 7.9 E^{5} \cdot Qb [mL / min] \cdot t [min]$	(6)
$I L 6 [pg / mL] = 1.48 + 0.00068 \cdot Dp [nm] + 0.005933 \cdot Qb [mL / min] - 0.0073 \cdot t [min] - 0.00031 \cdot Dp \cdot Qb [mL / min]$	(7)
$v W F [pg / mL] = 367.77 + 15.67 \cdot Dp [nm] + 1.48 \cdot Qb [mL / min]$	(8)