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. 2021 Nov;111(11):1950–1959. doi: 10.2105/AJPH.2021.306490

TABLE 2—

Cumulated Excess Deaths Rate per 100 000, All Causes, Pooled Cross-Sectional Time Series Analysis: 50 US States, February‒November 2020

Variables Cumulated Excess
Deaths, All Causesa
Coefficient (P)
Cumulated incident cases rate/100 000 0.01 (< .001)
 2000-unit increase 98 141
 4000-unit increase 196 282
 6000-unit increase 294 423
 8000-unit increase 392 564
 10 000-unit increase 490 705
Unemployment rate as proportion (%) of total labor force aged ≥ 16 years, seasonally adjusted 1.09 (< .001)
 5-unit increase 17 850
 10-unit increase 35 700
 15-unit increase 53 549
 20-unit increase 71 399
 25-unit increase 89 249
Cumulated total bankruptcies rate/100 000 0.37 (< .001)
 60-unit increase 72 242
 120-unit increase 144 483
 180-unit increase 216 725
 240-unit increase 288 967
 300-unit increase 361 208
Percentage of population aged ≥ 75 years, July 1, 2019, estimate 7.99 (.015)
 1-unit increase 26 243
 2-unit increase 52 485
 3-unit increase 78 728
 4-unit increase 104 971
 5-unit increase 131 213
Percentage of Black or African not Hispanic or Latino, July 1, 2019, estimate 0.48 (.14)
 5-unit increase 7 911
 10-unit increase 15 822
 20-unit increase 31 643
 30-unit increase 47 465
 40-unit increase 63 286
Percentage of White Hispanic or Latino, July 1, 2019, estimate 0.42 (.16)
 5-unit increase 6 846
 10-unit increase 13 692
 20-unit increase 27 385
 30-unit increase 41 077
 40-unit increase 54 770
Constant −73.19 (.003)

Note. Data show expected additional excess deaths, all causes, when the independent variable increases by the specified units. The estimated coefficients from the excess deaths model were used to calculate the associated change of the cumulated excess deaths rate, all causes. Based on the total US population from the year 2019, the change of the cumulated excess death rate was converted to expected additional excess deaths numbers (e.g., a change of the unemployment rate by absolute 10% results in 35 700 additional excess deaths). Analogously, when the cumulated bankruptcies rate per 100 000 changes by 120 units, then this will result in 144 483 additional excess deaths. The potential changes of the independent variables were derived by inspection of the descriptive statistics for each variable. Data and their sources of control variables are listed in Appendix B (available as a supplement to the online version of this article at http://www.ajph.org). For all key variables, a summary of descriptive statistics is provided in Appendix E (available as a supplement to the online version of this article at http://www.ajph.org).

a

Estimates for excess deaths were based on a 2019 US population of 328 239 523. The number of observations for the analysis was n = 500; R2 = .62; Wald χ2(5) (Prob > χ2) = 2053.66 (P < .001).